abcam ab6401-Anti-pan Cytokeratin antibody PCK-26 鼠单克隆[PCK-26

abcam ab6401-Anti-pan Cytokeratin antibody PCK-26 鼠单克隆[PCK-26

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abcam ab6401-Anti-pan Cytokeratin antibody PCK-26 鼠单克隆[PCK-26

Anti-pan Cytokeratin antibody [PCK-26] 鼠单克隆[PCK-26 

Form

Liquid

Storage instructions

Store at +4°C short term （1-2 weeks）. Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Ascites

Concentration

 

Anti-pan Cytokeratin antibody [PCK-26] 鼠单克隆[PCK-26 

 

Purity

Ascites

Clonality

Monoclonal

Clone number

PCK-26

Myeloma

unknown

Isotype

IgG1

Light chain type

unknown

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Intermediate Filaments >> Class I >> Cytokeratins
 

• Datasheet PDF
• SDS

• Immunohistochemistry （Formalin/PFA-fixed paraffin-ded sections） - pan Cytokeratin antibody [PCK-26] （ab6401）（enlarge）

• Immunohistochemistry （Formalin/PFA-fixed paraffin-ded sections） - pan Cytokeratin antibody [PCK-26] （ab6401）（enlarge）

• Western blot - pan Cytokeratin antibody [PCK-26] （ab6401）（enlarge）

Applications

Show applications key

Our Abpromise guarantee covers the use of ab6401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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  WB

  Four stars（5 Abreviews）WB: Use at an assay depe...Read more →

  WB: Use at an assay dependent dilution.

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  IHC-FoFr

  IHC-FoFr: Use at an assa...Read more →

  IHC-FoFr: Use at an assay dependent dilution.

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  IHC-P

  Five stars（3 Abreviews）IHC-P: Use at an assay d...Read more →

  IHC-P: Use at an assay dependent dilution.

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  IHC-Fr

  Four stars（3 Abreviews）IHC-Fr: Use at an assay ...Read more →

  IHC-Fr: Use at an assay dependent dilution.

• IF

  IF: 1/300.

  IF: 1/300.

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  Dot Blot

  Dot: Use at an assay dep...Read more →

  Dot: Use at an assay dependent dilution.

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  Flow Cyt

  See more...Read more →

  Flow Cyt: Use at an assay dependent dilution. PubMed: 19855980Use 10µl for 5 x 10⁷ cells.

• 2 Images

  ICC/IF

  Five stars（2 Abreviews）ICC/IF: 1/300.

  ICC/IF: 1/300.

Target

Relevance

Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin （mixture） is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, plastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting microstases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.

Cellular localization

Cytoplasmic

Anti-pan Cytokeratin antibody [PCK-26] images:

 

Immunohistochemistry （Formalin/PFA-fixed paraffin-ded sections） - pan Cytokeratin antibody [PCK-26] （ab6401）