
订货号:AF-100-18B
Animal-Free Recombinant Human FGF-basic (154 a.a.)是由上海肯强供应,产品价格优惠,欢迎致电我公司。 手机: QQ:1026257835 邮箱:1026257835@qq.com
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Animal-Free Recombinant Human FGF-basic (154 a.a.)
Catalog Number:
AF-100-18B
Synonyms:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
De
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
Qualified for stem cell use.
Manufactured using all Animal-Free reagents.
AA Sequence:
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Cross Reactivity:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Chicken, Horse, N/A, Human + Virus, Salamander
Research Interests:
| Angiogenesis/ Cardiovascular | Cell Culture |
| FGF Superfamily | Inflammation |
| Neurobiology | Proliferation |
| Stem Cells & Differentiation | Wound Healing |
