Animal Free Recombinant Human FGF basic 154 a a peprotech-AF-100-18B

发布时间:2017-07-06

订货号:AF-100-18B

Animal-Free Recombinant Human FGF-basic (154 a.a.)是由上海肯强供应,产品价格优惠,欢迎致电我公司。 手机: QQ:1026257835 邮箱:1026257835@qq.com

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Animal-Free Recombinant Human FGF-basic (154 a.a.)

Catalog Number:

AF-100-18B

Synonyms:

Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin

Deion:

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.

Qualified for stem cell use.

Manufactured using all Animal-Free reagents.

AA Sequence:

AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS

Source:

E.coli

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Cross Reactivity:

Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Chicken, Horse, N/A, Human + Virus, Salamander

Research Interests:

Angiogenesis/ Cardiovascular Cell Culture
FGF Superfamily Inflammation
Neurobiology Proliferation
Stem Cells & Differentiation Wound Healing
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