Rabbit Anti- FAT tumor suppressor homolog 1(FAT1) polyclonal Antibody

发布时间:2018-01-23

Quantity size:   0.1ml  (200ug/ml Lyophilized or Liquid. Buffer = 0.01M PBS pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide. Reconstitute with 0.2ml sterile distilled water.)

            

Background:   Fat 1 is a protein that in humans is encoded by the FAT1 gene. This gene is an ortholog of the Drosophila fat gene which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor and is likely to be important in developmental processes and cell communication. Tran variants derived from alternative splicing and/or alternative promoter usage exist but they have not been fully described.

Specificity:      Rabbit anti- FAT tumor suppressor homolog 1(FAT1) polyclonalAntibody.

Reacts with:  Human

 

 

Application:     ELISA=1:500-1000 

IHC-P=1:100-500 

IHC-F=1:100-500 

                IF=1:50-200  

                WB=1:20-200

                Not yet tested in other applications.

                Optimal working dilutions must be determined by the end user.

            

Storage: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The Lyophilized or Liquid antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 °C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note: This product as supplied is intended for research use only not for use in human therapeutic or diagnostic applications.

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