订货号:100-32
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Recombinant Human FGF-19
Catalog Number:
100-32
Synonyms:
Fibroblast Growth Factor-19, FGFJ
De
The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high-affinity heparin-dependent ligand for FGFR4. FGF-19 is expressed during brain development and embryogenesis. Recombinant Human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.
AA Sequence:
MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.
Cross Reactivity:
Mouse, Hamster, N/A
Research Interests:
Angiogenesis/ Cardiovascular | Bone, Skeletal, Cartilage |
FGF Superfamily | Proliferation |
Stem Cells & Differentiation |