订货号：AF-250-03
Animal-Free Recombinant Murine SCF是由上海肯强供应，产品价格优惠，欢迎致电我公司。 手机： QQ：1026257835 邮箱：1026257835@qq.com
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Animal-Free Recombinant Murine SCF
Catalog Number：
AF-250-03
Synonyms：
Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor
De
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. The human SCF gene encodes for a 273 amino acid transmembrane protein, which contains a 25 amino acid N-terminal signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. The secreted soluble form of SCF is generated by proteolytic processing of the membrane anchored precursor. Recombinant Murine SCF is an 18.3 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Manufactured using all Animal-Free reagents.
AA Sequence：
MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
Source：
E.coli
Purity：
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity：
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 10.0 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Cross Reactivity：
Human, Monkey, Rat, Mouse
Research Interests：
| Cell Culture | Immune System |
| Proliferation | Stem Cells & Differentiation |
