Rabbit anti-IL 3R alpha/CD123 抗体免疫组化wb说明书

Rabbit anti-IL 3R alpha/CD123

From: Santa Cruz

 

Cat. Number: Rs-2600R

 

Quantity size: 0.1ml (dilute with pH 7.4 0.01 M PBS or diluent of antibody)

 

Background: The protein encoded by this gene is an interleukin 3 specific subunit oheterodimeric cytokine receptor. The receptor is comprised of a ligand specalpha subunit and a signal transducing beta subunit shared by the receptors interleukin 3 (IL3) colony stimulating factor 2 (CSF2/GM-CSF) and interleukin(IL5). The binding of this protein to IL3 depends on the beta subunit. The bsubunit is activated by the ligand binding and is required for the biological activitof IL3. This gene and the gene encoding the colony stimulating factor 2 recepalpha chain (CSF2RA) form a cytokine receptor gene cluster in a Xpseudoautosomal region on chromosomes X or Y.

 

Also known as: Interleukin-3 receptor subunit alpha precursor; CD 123; CD123; CD123 antighIL3Ra; IL 3 receptor subunit alpha; IL 3R alpha; IL 3R; IL 3R subunit alpha; receptor subunit alpha; IL3R alpha; IL3R; IL3RAY; IL3RX; IL3RY; Interleukinreceptor alpha; Interleukin 3 receptor alpha (low affinity); Interleukin-3 recep MGC34174.

 

Specificity: · anti- IL 3R alpha is a rabbit polyclonal antibody unconjugated

· specific for IL 3R alpha of human

· epitope mapping near the amino terminus of IL 3R alpha of human origin

· use for western blotting elisa immunoprecipitation and immunohistochemist

· affinity chromatography purification purity :>95% Isotype: IgG

· mol wt:42kDa

 

Rabbit anti-IL 3R alpha/CD123

Application: · Western blotting: 1:100-500

· Immunohistochemistry: 1:100-500

· ELISA: 1:500-1000

· Optimal working dilutions must be determined by the end user.

 

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.

 

Important Note: This product as supplied is intended for research use only not for use in human therapeutic or diagnostic applications.