Recombinant Human FGF-4

 Deion:

FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.

AA Sequence:

GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL

Source:

E.coli

Purity:

Greater than 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶units/mg.

 

 

 

 

Cross Reactivity:

Mouse, Rat, Human, N/A, Pig

Research Interests:

	Angiogenesis/ Cardiovascular		FGF Superfamily
	Proliferation		Stem Cells & Differentiation

 

 

Country of Origin:

USA

Research Use Only. Not for use in diagnostic or therapeutic procedures.