SC-221689-santacruz GSK-3 Inhibitor X，SC-221689-santacruz GSK-3 Inhibitor X，SC-221689-santacruz GSK-3 Inhibitor X

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SC-221689-santacruz GSK-3 Inhibitor X，SC-221689-santacruz GSK-3 Inhibitor X，SC-221689-santacruz GSK-3 Inhibitor X

 

santacruz GSK-3 Inhibitor X
santacruz GSK-3 Inhibitor X详细产品信息：

GSK-3 Inhibitor X (CAS 740841-15-0)

5 5 (Based on popularity) 1 Synonym: BIO-Acetoxime; 6-Bromoindirubin-3′-acetoxime, BIA Application: A selective GSK-3α/β inhibitor CAS Number: 740841-15-0 Purity: ≥95% Molecular Weight: 398.21 Molecular Formula: C18H12BrN3O3 Refer to Certificate of Analysis for lot specific data (including water content). Set Currency US DollarsEuroSwiss FrancsBritish PoundsAustralia DollarsCanadian DollarsRMB Add Selected    Ordering Information Product Name Catalog # Unit Price Qty Add Favorites GSK-3 Inhibitor X sc-221689 1 mg $115   Add   Deion GSK-3 Inhibitor X is an acetoxime analog of BIO which acts as a selective GSK-3α/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). GSK-3 Inhibitor X induces Wnt signaling and inhibits CD8+ T cell effector differentiation. Technical Information Physical State: Solid Solubility: Soluble in DMSO (10 mg/ml). Storage: Store at 4° C Melting Point: 236.83 °C (Predicted) Boiling Point: 551.87 °C (Predicted) Density: 1.69 g/cm3 (Predicted) Refractive Index: n20D 1.74 (Predicted) IC50: GSK-3α/β: IC50 = 10 nM; Cdk5/p25: IC50 = 2.4 µM; Cdk2/A: IC50 = 4.3 µM; Cdk1/B: IC50 = 63 µM; Cdk4/D1: IC50 = ≥10 µM; aryl hydrocarbon receptor: EC5050 = ≥0.1 µM (yeast); aryl hydrocarbon receptor: EC5050 = 0.16 µM (mammalian) pK Values: pKa: 9.23 (Predicted) Safety and Reference Information PubChem CID: 6538818 MDL Number: MFCD09037533 SMILES: CC(=O)ONC1=C2C=CC=CC2=NC1=C3C4=C(C=C(C=C4)Br)NC3=O For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

santacruz GSK-3 Inhibitor X
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