PTBP2/Biotin 抗体antibody

                Anti-PTBP2/Biotin 抗体antibody

From:Santa

Catalog Number : sc-101183

Quantity size :   0.1ml  (dilute with pH 7.4    0.01 M PBS or antibody diluent ) Background: PTBP-2 is a member of the polypyrimidine tract binding family of proteins. Predominantly expressed in brain but also found in heart and skeletal muscle PTBP-2 localizes to the nucleus and contains four RRM (RNA recognition motif) domains. PTBP-2 functions as an RNA-binding protein associated in a complex that is involved in the regulation of exon splicing and the stabilization of mRNAs in the cytoplasm. Six isoforms exist for PTBP-2 due to alternative splicing events. Isoforms 1 and 2 (also known as nPTB1 and nPTB2/PTBPLP-L respectively) are neuronal-specific. Isoforms 3 and 4 (also known as nPTB3/PTBPLP-L and nPTB4 respectively) are found in non-neuronal tissues as are isoforms 5 and 6 (also known as nPTB5/nPTB7/PTBPLP-S and nPTB6/nPTB8/PTBPLP-S respectively). The existence of various isoforms may function to modulate the RNA-binding properties of PTBP-2

• Specificity : Anti-PTBP2 a  mouse monoclonal antibody               
• specific for PTBP2 of Human origin
• use for western blottingelisaimmunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification purity :>95%
• Isotype:  IgG
• mol wt:  57kDa

Application :  

• WB=1:50-200  ELISA=1:100-1000  IHC-P=1:50-200  IHC-F=1:50-200  IF=1:50-200
• not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user..

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody the antibody is stable for at least six weeks at 2-4 ℃

 

Important Note: This product as supplied is intended for research use only not for use in  human therapeutic or diagnostic applications.