Rabbit Anti-XAF1 (XIAP-associated factor 1)

  Rabbit Anti-XAF1 (XIAP-associated factor 1)

FROM：Santa Cruz
Catalog Number :Rs-1308R

Quantity size :0.1ml (dilute with pH 7.4 0.01 M PBS or antibody diluent )
Background: X-ed inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases(e.g. CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells

 

Specificity :  · anti- XAF1 is a Rabbit monoclonal antibody unconjugated

· specific for XAF1 of hu mo rat

· epitope mapping near the N-terminus of XAF1 of hu mo rat

· use for western blotting elisa immunoprecipitation

and immunohistochemistry

· Protein G affinity chromatography purification purity :>95%

· Isotype: IgG

· mol wt:32kDa
 

  Rabbit Anti-XAF1 (XIAP-associated factor 1)

Application:  · Western blotting 1:100-500

· Immunohistochemistry 1:100-500

· ELISA 1:500-1000

· Optimal working dilutions must be determined by the end user.
 

Storage: Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only not for use in human therapeutic or diagnostic applications.

   Rabbit Anti-XAF1 (XIAP-associated factor 1)